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Promotion of β-Catenin/Forkhead Box Protein O Signaling Mediates Epithelial Repair in Kidney Injury

Fibrosis is characterized by progressively excessive deposition of matrix components and may lead to organ failure. Transforming growth factor-β (TGF-β) is a key cytokine involved in tissue repair and fibrosis. TGF-β′s profibrotic signaling pathways converge at activation of β-catenin. β-Catenin is...

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Detalles Bibliográficos
Autores principales: Rao, Padmashree, Qiao, Xi, Hua, Winston, Hu, Min, Tahan, Mariah, Chen, Titi, Yu, Hong, Ren, Xiaojun, Cao, Qi, Wang, Yiping, Yang, Ying, Wang, Yuan M., Lee, Vincent W., Alexander, Stephen I., Harris, David C., Zheng, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351131/
https://www.ncbi.nlm.nih.gov/pubmed/33753026
http://dx.doi.org/10.1016/j.ajpath.2021.03.005