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Collagen-VI supplementation by cell transplantation improves muscle regeneration in Ullrich congenital muscular dystrophy model mice

BACKGROUND: Mesenchymal stromal cells (MSCs) function as supportive cells on skeletal muscle homeostasis through several secretory factors including type 6 collagen (COL6). Several mutations of COL6A1, 2, and 3 genes cause Ullrich congenital muscular dystrophy (UCMD). Skeletal muscle regeneration de...

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Detalles Bibliográficos
Autores principales: Takenaka-Ninagawa, Nana, Kim, Jinsol, Zhao, Mingming, Sato, Masae, Jonouchi, Tatsuya, Goto, Megumi, Yoshioka, Clémence Kiho Bourgeois, Ikeda, Rukia, Harada, Aya, Sato, Takahiko, Ikeya, Makoto, Uezumi, Akiyoshi, Nakatani, Masashi, Noguchi, Satoru, Sakurai, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351132/
https://www.ncbi.nlm.nih.gov/pubmed/34372931
http://dx.doi.org/10.1186/s13287-021-02514-3