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CYB561D2 up-regulation activates STAT3 to induce immunosuppression and aggression in gliomas

BACKGROUND: Fine tuned balance of reactive oxygen species (ROS) is essential for tumor cells and tumor cells use immune checkpoints to evade attack form immunity system. However, it’s unclear whether there is any crosstalk between these two pathways. CYB561D2, an antioxidant protein, is part of 5-ge...

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Detalles Bibliográficos
Autores principales: Tao, Bangbao, Shi, Juanhong, Shuai, Shuai, Zhou, Haiyan, Zhang, Hongxia, Li, Bin, Wang, Xiaoqiang, Li, Guohui, He, Hua, Zhong, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351164/
https://www.ncbi.nlm.nih.gov/pubmed/34372858
http://dx.doi.org/10.1186/s12967-021-02987-z