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BSCI-10. Invasive growth of brain metastases is driven by cancer cell-pSTAT3+ reactive astrocyte crosstalk

BACKGROUND: Brain metastases (BrM) with a highly invasive (HI) histological growth pattern are associated with poor prognosis compared to minimally invasive (MI) masses. Compared to MI lesions, HI BrM form greater contacts with cells in the peritumoral brain, particularly reactive astrocytes (RAs)....

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Detalles Bibliográficos
Autores principales: Dankner, Matthew, Maritan, Sarah, Zhuang, Rebecca, Caron, Maxime, Priego, Neibla, Valiente, Manuel, Petrecca, Kevin, Siegel, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351176/
http://dx.doi.org/10.1093/noajnl/vdab071.009