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BSCI-10. Invasive growth of brain metastases is driven by cancer cell-pSTAT3+ reactive astrocyte crosstalk
BACKGROUND: Brain metastases (BrM) with a highly invasive (HI) histological growth pattern are associated with poor prognosis compared to minimally invasive (MI) masses. Compared to MI lesions, HI BrM form greater contacts with cells in the peritumoral brain, particularly reactive astrocytes (RAs)....
Autores principales: | Dankner, Matthew, Maritan, Sarah, Zhuang, Rebecca, Caron, Maxime, Priego, Neibla, Valiente, Manuel, Petrecca, Kevin, Siegel, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351176/ http://dx.doi.org/10.1093/noajnl/vdab071.009 |
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