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OTHR-14. An immunogenomic analysis of melanoma brain metastases (MBM) compared to extracranial metastases (ECM)

BACKGROUND: MBM have a unique molecular profile compared to ECM. METHODS: We analyzed a previously published dataset from MD Anderson Cancer Center, including RNA-seq on surgically resected, FFPE MBM and ECM from the same patients. STAR pipeline was used to estimate mRNA abundance. DESeq2 package wa...

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Detalles Bibliográficos
Autores principales: Kennedy, Lucy Boyce, Van Swearingen, Amanda E D, Sheng, Jeff, Zhang, Dadong, Qin, Xiaodi, Lipp, Eric, Kumar, Swaminathan, Zhang, Gao, Hanks, Brent, Davies, Michael, Owzar, Kouros, Anders, Carey K, Salama, April K S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351192/
http://dx.doi.org/10.1093/noajnl/vdab071.069