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LMD-12. Ubiquitin Conjugating Enzymes promote leptomeningeal dissemination and decrease survival in patients with brain metastatic disease

The dissemination of cancer cells to the brain parenchyma (brain metastases - BMs) and to the leptomeninges (leptomeningeal dissemination – LD) are a late-stage complication of systemic cancers, with a poor survival. Despite advances in radiation and chemotherapy, including intrathecal administratio...

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Detalles Bibliográficos
Autores principales: Paisana, Eunice, Cascão, Rita, Custódia, Carlos, Qin, Nan, Picard, Daniel, Pauck, David, Carvalho, Tânia, Ruivo, Pedro, Pereira, Pedro, Roque, Rafael, Pimentel, José, Miguéns, José, Remke, Marc, Barata, João T, Faria, Claudia C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351197/
http://dx.doi.org/10.1093/noajnl/vdab071.037