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LMD-18. Detection and serial monitoring of CSF ctDNA in breast cancer leptomeningeal disease (BCLM)

BACKGROUND: CSF cytology is the gold standard diagnostic test for BCLM, but is hampered by a low sensitivity, often necessitating repeated lumbar puncture to confirm or refute the diagnosis. Furthermore, during the treatment of BCLM, there is no robust quantitative response tool to guide treatment d...

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Detalles Bibliográficos
Autores principales: Fitzpatrick, Amanda, Iravani, Marjan, Okines, Alicia, Mills, Adam, Harries, Mark, Tutt, Andrew, Isacke, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351201/
http://dx.doi.org/10.1093/noajnl/vdab071.043