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Bcl-2-associated transcription factor 1 Ser290 phosphorylation mediates DNA damage response and regulates radiosensitivity in gastric cancer

BACKGROUND: DNA damage response plays critical roles in tumor pathogenesis and radiotherapy resistance. Protein phosphorylation is a critical mechanism in regulation of DNA damage response; however, the key mediators for radiosensitivity in gastric cancer still needs further exploration. METHODS: A...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Li, Jingyi, Sun, Zhao, Duan, Yangmiao, Wang, Fengqin, Wei, Guangwei, Yang, Jing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351323/
https://www.ncbi.nlm.nih.gov/pubmed/34372878
http://dx.doi.org/10.1186/s12967-021-03004-z