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IDO Inhibition Facilitates Antitumor Immunity of Vγ9Vδ2 T Cells in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) escape from immune-mediated destruction was associated with immunosuppressive responses that dampened the activation of tumor-infiltrating CD8 and γδ T cells. TNBC had a higher level of programmed cell death 1-ligand 1 (PD-L1) and indoleamine 2,3-dioxygenase (IDO...

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Detalles Bibliográficos
Autores principales: Li, Peng, Wu, Ruan, Li, Ke, Yuan, Wenhui, Zeng, Chuqian, Zhang, Yuting, Wang, Xiao, Zhu, Xinhai, Zhou, Jianjun, Li, Ping, Gao, Yunfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351331/
https://www.ncbi.nlm.nih.gov/pubmed/34381711
http://dx.doi.org/10.3389/fonc.2021.679517