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Effects of simvastatin on white matter integrity in healthy middle‐aged adults

BACKGROUND: The brain is the most cholesterol‐rich organ and myelin contains 70% of total brain cholesterol. Statins are potent cholesterol‐lowing medications used by millions of adults for prevention of vascular disease, yet the effect of statins on cholesterol‐rich brain white matter (WM) is large...

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Detalles Bibliográficos
Autores principales: Vogt, Nicholas M., Hunt, Jack F. V., Ma, Yue, Van Hulle, Carol A., Adluru, Nagesh, Chappell, Richard J., Lazar, Karen K., Jacobson, Laura E, Austin, Benjamin P., Asthana, Sanjay, Johnson, Sterling C., Bendlin, Barbara B., Carlsson, Cynthia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351379/
https://www.ncbi.nlm.nih.gov/pubmed/34275209
http://dx.doi.org/10.1002/acn3.51421