Cargando…

ME2 Promotes Proneural–Mesenchymal Transition and Lipogenesis in Glioblastoma

Malic enzyme 2 (ME2) catalyzes the formation of pyruvate from malic acid and is abnormally expressed in some tumors. However, the exact effects of ME2 on proneural–mesenchymal transition (PMT) and lipogenesis in glioblastoma multiforme (GBM) remain unexplored. Here, we found that ME2 expression was...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Mengting, Chen, Xi, Zhang, Junyao, Xiong, Ermeng, Wang, Qianqian, Fang, Wenjing, Li, Li, Fei, Fei, Gong, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351415/
https://www.ncbi.nlm.nih.gov/pubmed/34381734
http://dx.doi.org/10.3389/fonc.2021.715593