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Using a new HSPC senescence model in vitro to explore the mechanism of cellular memory in aging HSPCs
BACKGROUND: Age-associated changes attenuate human blood system functionality through the aging of hematopoietic stem and progenitor cells (HSPCs), manifested in human populations an increase in myeloproliferative disease and even leukemia; therefore, study on HSPC senescence bears great significanc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351417/ https://www.ncbi.nlm.nih.gov/pubmed/34365970 http://dx.doi.org/10.1186/s13287-021-02455-x |