Copper–ligand clusters dictate size of cyclized peptide formed during alkyne–azide cycloaddition on solid support

Peptide and peptidomimetic cyclization by copper-catalyzed alkyne–azide cycloaddition (CuAAC) reaction have been used to mimic disulfide bonds, alpha helices, amide bonds, and for one-bead-one-compound (OBOC) library development. A limited number of solid-supported CuAAC cyclization methods resultin...

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Detalles Bibliográficos
Autores principales: Kandler, Rene, Das, Samir, Nag, Arundhati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351437/
https://www.ncbi.nlm.nih.gov/pubmed/34377440
http://dx.doi.org/10.1039/d0ra07491h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351437/
https://www.ncbi.nlm.nih.gov/pubmed/34377440
http://dx.doi.org/10.1039/d0ra07491h

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