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SIRT1/PGC-1α/PPAR-γ Correlate With Hypoxia-Induced Chemoresistance in Non-Small Cell Lung Cancer

Resistance is the major cause of treatment failure and disease progression in non-small cell lung cancer (NSCLC). There is evidence that hypoxia is a key microenvironmental stress associated with resistance to cisplatin, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), and...

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Detalles Bibliográficos
Autores principales: Xu, Rui, Luo, Xin, Ye, Xuan, Li, Huan, Liu, Hongyue, Du, Qiong, Zhai, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351465/
https://www.ncbi.nlm.nih.gov/pubmed/34381712
http://dx.doi.org/10.3389/fonc.2021.682762