LncRNA nuclear‐enriched abundant transcript 1 shuttled by prostate cancer cells‐secreted exosomes initiates osteoblastic phenotypes in the bone metastatic microenvironment via miR‐205‐5p/runt‐related transcription factor 2/splicing factor proline‐ and glutamine‐rich/polypyrimidine tract‐binding protein 2 axis

Prostate cancer (PCa) patients commonly present with osteoblastic‐type bone metastasis. Exosomes derived from tumor cells possess biological significance and can mediate intercellular communication in the tumor microenvironment. Long noncoding RNA (lncRNA) nuclear‐enriched abundant transcript 1 (NEA...

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Detalles Bibliográficos
Autores principales: Mo, Chengqiang, Huang, Bin, Zhuang, Jintao, Jiang, Shuangjian, Guo, Shengjie, Mao, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351523/
https://www.ncbi.nlm.nih.gov/pubmed/34459124
http://dx.doi.org/10.1002/ctm2.493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351523/
https://www.ncbi.nlm.nih.gov/pubmed/34459124
http://dx.doi.org/10.1002/ctm2.493

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