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Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons
The dependence of neurons on microtubule-based motors for the movement of lysosomes over long distances raises questions about adaptations that allow neurons to meet these demands. Recently, JIP3/MAPK8IP3, a neuronally enriched putative adaptor between lysosomes and motors, was identified as a criti...
Autores principales: | Gowrishankar, Swetha, Lyons, Lila, Rafiq, Nisha Mohd, Roczniak-Ferguson, Agnes, De Camilli, Pietro, Ferguson, Shawn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351540/ https://www.ncbi.nlm.nih.gov/pubmed/33788575 http://dx.doi.org/10.1091/mbc.E20-06-0382 |
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