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Spatial proximity of proteins surrounding zyxin under force-bearing conditions

Sensing physical forces is a critical first step in mechano-transduction of cells. Zyxin, a LIM domain-containing protein, is recruited to force-bearing actin filaments and is thought to repair and strengthen them. Yet, the precise force-induced protein interactions surrounding zyxin remain unclear....

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Detalles Bibliográficos
Autores principales: Cheah, Joleen S., Jacobs, Kyle A., Lai, Tzu Wei, Caballelo, Reca, Yee, Jacqueline L., Ueda, Shuji, Heinrich, Volkmar, Yamada, Soichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351546/
https://www.ncbi.nlm.nih.gov/pubmed/33909446
http://dx.doi.org/10.1091/mbc.E19-10-0568