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Multiple C2 domain–containing transmembrane proteins promote lipid droplet biogenesis and growth at specialized endoplasmic reticulum subdomains

Lipid droplets (LDs) are neutral lipid-containing organelles enclosed in a single monolayer of phospholipids. LD formation begins with the accumulation of neutral lipids within the bilayer of the endoplasmic reticulum (ER) membrane. It is not known how the sites of formation of nascent LDs in the ER...

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Detalles Bibliográficos
Autores principales: Joshi, Amit S., Ragusa, Joey V., Prinz, William A., Cohen, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351558/
https://www.ncbi.nlm.nih.gov/pubmed/33826368
http://dx.doi.org/10.1091/mbc.E20-09-0590