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The N-terminal tail of C. elegans CENP-A interacts with KNL-2 and is essential for centromeric chromatin assembly

Centromeres are epigenetically defined by the centromere-specific histone H3 variant CENP-A. Specialized loading machinery, including the histone chaperone HJURP/Scm3, participates in CENP-A nucleosome assembly. However, Scm3/HJURP is missing from multiple lineages, including nematodes, with CENP-A-...

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Detalles Bibliográficos
Autores principales: de Groot, Christian, Houston, Jack, Davis, Bethany, Gerson-Gurwitz, Adina, Monen, Joost, Lara-Gonzalez, Pablo, Oegema, Karen, Shiau, Andrew K., Desai, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351560/
https://www.ncbi.nlm.nih.gov/pubmed/33852350
http://dx.doi.org/10.1091/mbc.E20-12-0798