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Protein turnover dynamics suggest a diffusion-to-capture mechanism for peri-basal body recruitment and retention of intraflagellar transport proteins

Intraflagellar transport (IFT) is essential for construction and maintenance of cilia. IFT proteins concentrate at the basal body where they are thought to assemble into trains and bind cargoes for transport. To study the mechanisms of IFT recruitment to this peri-basal body pool, we quantified prot...

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Detalles Bibliográficos
Autores principales: Hibbard, Jaime V. K., Vazquez, Neftali, Satija, Rohit, Wallingford, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351562/
https://www.ncbi.nlm.nih.gov/pubmed/33826363
http://dx.doi.org/10.1091/mbc.E20-11-0717