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Implication of integrin α2β1 in senescence of SK-Mel-147 human melanoma cells

This investigation addressed the impact of integrin-initiated signaling pathways on senescence of tumor cells. In a model of human SK-Mel-147 melanoma cells, the silencing of integrin α2β1 strongly reduced cell proliferation and enhanced the percentage of SA-β-Gal-positive cells, a phenotypic featur...

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Detalles Bibliográficos
Autores principales: Kozlova, Nadezhda I., Morozevich, Galina E., Berman, Albert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351665/
https://www.ncbi.nlm.nih.gov/pubmed/34257160
http://dx.doi.org/10.18632/aging.203309