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Regulation of the IGF1 signaling pathway is involved in idiopathic pulmonary fibrosis induced by alveolar epithelial cell senescence and core fucosylation

Idiopathic pulmonary fibrosis (IPF) mainly occurs in elderly people over the age of sixty. IPF pathogenesis is associated with alveolar epithelial cells (AECs) senescence. Activation of PI3K/AKT signaling induced by insulin-like growth factor 1 (IGF1) participates in AEC senescence and IPF by releas...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Jing, Xiaoyan, Yang, Xiaoyu, Huang, Hui, Luo, Qun, Xia, Shu, Wang, Ping, Wang, Na, Zhang, Qian, Guo, Jian, Xu, Zuojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351684/
https://www.ncbi.nlm.nih.gov/pubmed/34329195
http://dx.doi.org/10.18632/aging.203335