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BMI1 activates P-glycoprotein via transcription repression of miR-3682-3p and enhances chemoresistance of bladder cancer cell

Chemoresistance is the most significant reason for the failure of cancer treatment following radical cystectomy. The response rate to the first-line chemotherapy of cisplatin and gemcitabine does not exceed 50%. In our previous research, elevated BMI1 (B-cell specific Moloney murine leukemia virus i...

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Detalles Bibliográficos
Autores principales: Chen, Ming-Kun, Zhou, Jun-Hao, Wang, Peng, Ye, Yun-lin, Liu, Yang, Zhou, Jia-Wei, Chen, Zi-Jian, Yang, Jian-Kun, Liao, De-Ying, Liang, Zhi-Jian, Xie, Xiao, Zhou, Qi-Zhao, Xue, Kang-Yi, Guo, Wen-Bin, Xia, Ming, Bao, Ji-Ming, Yang, Cheng, Duan, Hai-Feng, Wang, Hong-Yi, Huang, Zhi-Peng, Qin, Zi-Ke, Liu, Cun-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351696/
https://www.ncbi.nlm.nih.gov/pubmed/34270461
http://dx.doi.org/10.18632/aging.203277