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BMI1 activates P-glycoprotein via transcription repression of miR-3682-3p and enhances chemoresistance of bladder cancer cell
Chemoresistance is the most significant reason for the failure of cancer treatment following radical cystectomy. The response rate to the first-line chemotherapy of cisplatin and gemcitabine does not exceed 50%. In our previous research, elevated BMI1 (B-cell specific Moloney murine leukemia virus i...
Autores principales: | Chen, Ming-Kun, Zhou, Jun-Hao, Wang, Peng, Ye, Yun-lin, Liu, Yang, Zhou, Jia-Wei, Chen, Zi-Jian, Yang, Jian-Kun, Liao, De-Ying, Liang, Zhi-Jian, Xie, Xiao, Zhou, Qi-Zhao, Xue, Kang-Yi, Guo, Wen-Bin, Xia, Ming, Bao, Ji-Ming, Yang, Cheng, Duan, Hai-Feng, Wang, Hong-Yi, Huang, Zhi-Peng, Qin, Zi-Ke, Liu, Cun-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351696/ https://www.ncbi.nlm.nih.gov/pubmed/34270461 http://dx.doi.org/10.18632/aging.203277 |
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