GAS6 ameliorates advanced age-associated meiotic defects in mouse oocytes by modulating mitochondrial function

Previously, we reported that the silencing of growth arrest-specific gene 6 (Gas6) expression in oocytes impairs cytoplasmic maturation by suppressing mitophagy and inducing mitochondrial dysfunction, resulting in fertilization failure. Here, we show that oocyte aging is accompanied by an increase i...

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Detalles Bibliográficos
Autores principales: Kim, Kyeoung-Hwa, Kim, Eun-Young, Lee, Kyung-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351714/
https://www.ncbi.nlm.nih.gov/pubmed/34310342
http://dx.doi.org/10.18632/aging.203328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351714/
https://www.ncbi.nlm.nih.gov/pubmed/34310342
http://dx.doi.org/10.18632/aging.203328

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