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GAS6 ameliorates advanced age-associated meiotic defects in mouse oocytes by modulating mitochondrial function
Previously, we reported that the silencing of growth arrest-specific gene 6 (Gas6) expression in oocytes impairs cytoplasmic maturation by suppressing mitophagy and inducing mitochondrial dysfunction, resulting in fertilization failure. Here, we show that oocyte aging is accompanied by an increase i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351714/ https://www.ncbi.nlm.nih.gov/pubmed/34310342 http://dx.doi.org/10.18632/aging.203328 |