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Combination of rapamycin and SAHA enhanced radiosensitization by inducing autophagy and acetylation in NSCLC

Radiotherapy plays an essential role in the treatment of non-small-cell lung cancer (NSCLC). However, cancer cells' resistance to ionizing radiation (IR) is the primary reason for radiotherapy failure leading to tumor relapse and metastasis. DNA double-strand breaks (DSB) repair after IR is the...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Liu, Fen, Fang, Chen, Xu, Liyao, Chen, Lin, Xu, Zeyao, Chen, Jiaquan, Peng, Wei, Fu, Biqi, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351722/
https://www.ncbi.nlm.nih.gov/pubmed/34321364
http://dx.doi.org/10.18632/aging.203226