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Combination of rapamycin and SAHA enhanced radiosensitization by inducing autophagy and acetylation in NSCLC
Radiotherapy plays an essential role in the treatment of non-small-cell lung cancer (NSCLC). However, cancer cells' resistance to ionizing radiation (IR) is the primary reason for radiotherapy failure leading to tumor relapse and metastasis. DNA double-strand breaks (DSB) repair after IR is the...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351722/ https://www.ncbi.nlm.nih.gov/pubmed/34321364 http://dx.doi.org/10.18632/aging.203226 |