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Autophagy inhibition reinforces stemness together with exit from dormancy of polydisperse glioblastoma stem cells

Therapeutic resistance and infiltrative capacities justify the aggressiveness of glioblastoma. This is due to cellular heterogeneity, especially the presence of stemness-related cells, i.e. Cancer Stem Cells (CSC). Previous studies focused on autophagy and its role in CSCs maintenance; these studies...

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Detalles Bibliográficos
Autores principales: Brunel, Aude, Hombourger, Sophie, Barthout, Elodie, Battu, Serge, Kögel, Donat, Antonietti, Patrick, Deluche, Elise, Saada, Sofiane, Durand, Stéphanie, Lalloué, Fabrice, Jauberteau, Marie-Odile, Begaud, Gaëlle, Bessette, Barbara, Verdier, Mireille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351723/
https://www.ncbi.nlm.nih.gov/pubmed/34314381
http://dx.doi.org/10.18632/aging.203362