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HDAC2 and 7 down-regulation induces senescence in dermal fibroblasts

Originally simply reported to be in a stable and irreversible growth arrest in vitro, senescent cells are now clearly associated with normal and pathological ageing in vivo. They are characterized by several biomarkers and changes in gene expression that may depend on epigenetic factors, such as his...

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Detalles Bibliográficos
Autores principales: Warnon, Céline, Bouhjar, Karim, Ninane, Noëlle, Verhoyen, Mathilde, Fattaccioli, Antoine, Fransolet, Maude, Lambert de Rouvroit, Catherine, Poumay, Yves, Piel, Géraldine, Mottet, Denis, Debacq-Chainiaux, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351730/
https://www.ncbi.nlm.nih.gov/pubmed/34253688
http://dx.doi.org/10.18632/aging.203304