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The dynein light chain protein Tda2 functions as a dimerization engine to regulate actin capping protein during endocytosis

Clathrin- and actin-mediated endocytosis is a fundamental process in eukaryotic cells. Previously, we discovered Tda2 as a new yeast dynein light chain (DLC) that works with Aim21 to regulate actin assembly during endocytosis. Here we show Tda2 functions as a dimerization engine bringing two Aim21 m...

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Detalles Bibliográficos
Autores principales: Lamb, Andrew K., Fernandez, Andres N., Peersen,, Olve B., Di Pietro, Santiago M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351736/
https://www.ncbi.nlm.nih.gov/pubmed/34081539
http://dx.doi.org/10.1091/mbc.E21-01-0032