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A short C-terminal peptide in Gγ regulates Gβγ signaling efficacy

G protein beta-gamma (Gβγ) subunits anchor to the plasma membrane (PM) through the carboxy-terminal (CT) prenyl group in Gγ. This interaction is crucial for the PM localization and functioning of Gβγ, allowing GPCR-G protein signaling to proceed. The diverse Gγ family has 12 members, and we have rec...

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Detalles Bibliográficos
Autores principales: Tennakoon, Mithila, Senarath, Kanishka, Kankanamge, Dinesh, Chadee, Deborah N., Karunarathne, Ajith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351738/
https://www.ncbi.nlm.nih.gov/pubmed/34106735
http://dx.doi.org/10.1091/mbc.E20-11-0750