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Three-dimensional superresolution fluorescence microscopy maps the variable molecular architecture of the nuclear pore complex

Nuclear pore complexes (NPCs) are large macromolecular machines that mediate the traffic between the nucleus and the cytoplasm. In vertebrates, each NPC consists of ∼1000 proteins, termed nucleoporins, and has a mass of more than 100 MDa. While a pseudo-atomic static model of the central scaffold of...

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Detalles Bibliográficos
Autores principales: Sabinina, Vilma Jimenez, Hossain, M. Julius, Hériché, Jean-Karim, Hoess, Philipp, Nijmeijer, Bianca, Mosalaganti, Shyamal, Kueblbeck, Moritz, Callegari, Andrea, Szymborska, Anna, Beck, Martin, Ries, Jonas, Ellenberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351745/
https://www.ncbi.nlm.nih.gov/pubmed/34191541
http://dx.doi.org/10.1091/mbc.E20-11-0728