Cell adaptation to aneuploidy by the environmental stress response dampens induction of the cytosolic unfolded-protein response

Aneuploid yeast cells are in a chronic state of proteotoxicity, yet do not constitutively induce the cytosolic unfolded protein response, or heat shock response (HSR) by heat shock factor 1 (Hsf1). Here, we demonstrate that an active environmental stress response (ESR), a hallmark of aneuploidy acro...

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Detalles Bibliográficos
Autores principales: Kane, Andrew J., Brennan, Christopher M., Xu, Acer E., Solís, Eric J., Terhorst, Allegra, Denic, Vladimir, Amon, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351746/
https://www.ncbi.nlm.nih.gov/pubmed/34191542
http://dx.doi.org/10.1091/mbc.E21-03-0104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351746/
https://www.ncbi.nlm.nih.gov/pubmed/34191542
http://dx.doi.org/10.1091/mbc.E21-03-0104

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