Praja1 ubiquitin ligase facilitates degradation of polyglutamine proteins and suppresses polyglutamine-mediated toxicity

A network of chaperones and ubiquitin ligases sustain intracellular proteostasis and is integral in preventing aggregation of misfolded proteins associated with various neurodegenerative diseases. Using cell-based studies of polyglutamine (polyQ) diseases, spinocerebellar ataxia type 3 (SCA3) and Hu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghosh, Baijayanti, Karmakar, Susnata, Prasad, Mohit, Mandal, Atin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351749/
https://www.ncbi.nlm.nih.gov/pubmed/34161122
http://dx.doi.org/10.1091/mbc.E20-11-0747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351749/
https://www.ncbi.nlm.nih.gov/pubmed/34161122
http://dx.doi.org/10.1091/mbc.E20-11-0747

Ejemplares similares