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Praja1 ubiquitin ligase facilitates degradation of polyglutamine proteins and suppresses polyglutamine-mediated toxicity

A network of chaperones and ubiquitin ligases sustain intracellular proteostasis and is integral in preventing aggregation of misfolded proteins associated with various neurodegenerative diseases. Using cell-based studies of polyglutamine (polyQ) diseases, spinocerebellar ataxia type 3 (SCA3) and Hu...

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Detalles Bibliográficos
Autores principales:	Ghosh, Baijayanti, Karmakar, Susnata, Prasad, Mohit, Mandal, Atin K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351749/ https://www.ncbi.nlm.nih.gov/pubmed/34161122 http://dx.doi.org/10.1091/mbc.E20-11-0747

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