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Two-dimensional multiplexed assay for rapid and deep SARS-CoV-2 serology profiling and for machine learning prediction of neutralization capacity

Antibody responses serve as the primary protection against SARS-CoV-2 infection through neutralization of viral entry into cells. We have developed a two-dimensional multiplex bead binding assay (2D-MBBA) that quantifies multiple antibody isotypes against multiple antigens from a single measurement....

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Detalles Bibliográficos
Autores principales: Koide, Akiko, Panchenko, Tatyana, Wang, Chan, Thannickal, Sara A., Romero, Larizbeth A., Teng, Kai Wen, Li, Francesca-Zhoufan, Akkappedi, Padma, Corrado, Alexis D., Caro, Jessica, Diefenbach, Catherine, Samanovic, Marie I., Mulligan, Mark J., Hattori, Takamitsu, Stapleford, Kenneth A., Li, Huilin, Koide, Shohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351774/
https://www.ncbi.nlm.nih.gov/pubmed/34373852
http://dx.doi.org/10.1101/2021.08.03.454782