Cargando…

Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 responses

Nucleoside modified mRNA combined with Acuitas Therapeutics’ lipid nanoparticles (LNP) have been shown to support robust humoral immune responses in many preclinical animal vaccine studies and later in humans with the SARS-CoV-2 vaccination. We recently showed that this platform is highly inflammato...

Descripción completa

Detalles Bibliográficos
Autores principales: Ndeupen, Sonia, Bouteau, Aurélie, Herbst, Christopher, Qin, Zhen, Hutchins, Zachary, Kurup, Drishya, Diba, Leila Zabihi, Igyártó, Botond Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351776/
https://www.ncbi.nlm.nih.gov/pubmed/34373854
http://dx.doi.org/10.1101/2021.08.01.454662