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A Master Autoantigen-ome Links Alternative Splicing, Female Predilection, and COVID-19 to Autoimmune Diseases

Chronic and debilitating autoimmune sequelae pose a grave concern for the post-COVID-19 pandemic era. Based on our discovery that the glycosaminoglycan dermatan sulfate (DS) displays peculiar affinity to apoptotic cells and autoantigens (autoAgs) and that DS-autoAg complexes cooperatively stimulate...

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Detalles Bibliográficos
Autores principales: Wang, Julia Y., Roehrl, Michael W., Roehrl, Victor B., Roehrl, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351778/
https://www.ncbi.nlm.nih.gov/pubmed/34373855
http://dx.doi.org/10.1101/2021.07.30.454526