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Llamanade: an open-source computational pipeline for robust nanobody humanization

Nanobodies (Nbs) have recently emerged as a promising class of antibody fragments for biomedical and therapeutic applications. Despite having marked physicochemical properties, Nbs are derived from camelids and may require “humanization” to improve translational potentials for clinical trials. Here...

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Detalles Bibliográficos
Autores principales: Sang, Zhe, Xiang, Yufei, Bahar, Ivet, Shi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351782/
https://www.ncbi.nlm.nih.gov/pubmed/34373858
http://dx.doi.org/10.1101/2021.08.03.455003