Reduced Susceptibility to Metronidazole Is Associated With Initial Clinical Failure in Clostridioides difficile Infection

BACKGROUND: Clinical studies have demonstrated inferior cure rates when metronidazole (MTZ) is used to treat Clostridioides difficile infection (CDI). We hypothesized that a newly identified, heme-inducible form of reduced MTZ susceptibility in C. difficile leads to higher odds of initial clinical f...

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Detalles Bibliográficos
Autores principales: Gonzales-Luna, Anne J, Olaitan, Abiola O, Shen, Wan-Jou, Deshpande, Aditi, Carlson, Travis J, Dotson, Kierra M, Lancaster, Chris, Begum, Khurshida, Alam, M Jahangir, Hurdle, Julian G, Garey, Kevin W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Major Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351808/
https://www.ncbi.nlm.nih.gov/pubmed/34381844
http://dx.doi.org/10.1093/ofid/ofab365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351808/
https://www.ncbi.nlm.nih.gov/pubmed/34381844
http://dx.doi.org/10.1093/ofid/ofab365

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