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Transient suppression of transplanted spermatogonial stem cell differentiation restores fertility in mice

A remarkable feature of tissue stem cells is their ability to regenerate the structure and function of host tissue following transplantation. However, the dynamics of donor stem cells during regeneration remains largely unknown. Here we conducted quantitative clonal fate studies of transplanted mous...

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Detalles Bibliográficos
Autores principales: Nakamura, Yoshiaki, Jörg, David J., Kon, Yayoi, Simons, Benjamin D., Yoshida, Shosei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351876/
https://www.ncbi.nlm.nih.gov/pubmed/33848470
http://dx.doi.org/10.1016/j.stem.2021.03.016