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Mathematical modeling of N-803 treatment in SIV-infected non-human primates

Immunomodulatory drugs could contribute to a functional cure for Human Immunodeficiency Virus (HIV). Interleukin-15 (IL-15) promotes expansion and activation of CD8(+) T cell and natural killer (NK) cell populations. In one study, an IL-15 superagonist, N-803, suppressed Simian Immunodeficiency Viru...

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Detalles Bibliográficos
Autores principales: Cody, Jonathan W., Ellis-Connell, Amy L., O’Connor, Shelby L., Pienaar, Elsje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351941/
https://www.ncbi.nlm.nih.gov/pubmed/34319980
http://dx.doi.org/10.1371/journal.pcbi.1009204