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Neural differentiation of glioblastoma cell lines via a herpes simplex virus thymidine kinase/ganciclovir system driven by a glial fibrillary acidic protein promoter

Glioblastoma is a malignant brain tumor with poor prognosis that rapidly acquires resistance to available clinical treatments. The herpes simplex virus thymidine kinase/ganciclovir (HSVtk/GCV) system produces the selective elimination of HSVtk-positive cells and is a candidate for preclinical testin...

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Detalles Bibliográficos
Autores principales: Luo, Elizabeth Wei-Chia, Liao, Meng-Lin, Chien, Chung-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351974/
https://www.ncbi.nlm.nih.gov/pubmed/34370752
http://dx.doi.org/10.1371/journal.pone.0253008