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Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1-skewed proinflammatory immune responses

Orientia tsutsugamushi is an obligately intracellular bacterium and the etiological agent of scrub typhus. The lung is a major target organ of infection, displaying type 1-skewed proinflammatory responses. Lung injury and acute respiratory distress syndrome are common complications of severe scrub t...

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Detalles Bibliográficos
Autores principales: Fisher, James, Card, Galen, Liang, Yuejin, Trent, Brandon, Rosenzweig, Holly, Soong, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351992/
https://www.ncbi.nlm.nih.gov/pubmed/34320039
http://dx.doi.org/10.1371/journal.ppat.1009782