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Acute Effects of Ibrutinib on Ventricular Arrhythmia in Spontaneously Hypertensive Rats

BACKGROUND: The Bruton's Tyrosine Kinase Inhibitor ibrutinib is associated with ventricular arrhythmia (VA) and sudden death. However, the pro-arrhythmic electrophysiological dysregulation that results from ibrutinib with age and cardiovascular disease is unknown. OBJECTIVES: This study sought...

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Detalles Bibliográficos
Autores principales: Du, Beibei, Chakraborty, Praloy, Azam, Mohammed Ali, Massé, Stéphane, Lai, Patrick F.H., Niri, Ahmed, Si, Daoyuan, Thavendiranathan, Paaladinesh, Abdel-Qadir, Husam, Billia, Filio, Nanthakumar, Kumaraswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352013/
https://www.ncbi.nlm.nih.gov/pubmed/34396273
http://dx.doi.org/10.1016/j.jaccao.2020.08.012