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Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

BACKGROUND: The degree of heterotypic immunity induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains is a major determinant of the spread of emerging variants and the success of vaccination campaigns, but remains incompletely understood. METHODS: We examined the immunogenic...

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Detalles Bibliográficos
Autores principales: Faulkner, Nikhil, Ng, Kevin W, Wu, Mary Y, Harvey, Ruth, Margaritis, Marios, Paraskevopoulou, Stavroula, Houlihan, Catherine, Hussain, Saira, Greco, Maria, Bolland, William, Warchal, Scott, Heaney, Judith, Rickman, Hannah, Spyer, Moria, Frampton, Daniel, Byott, Matthew, de Oliveira, Tulio, Sigal, Alex, Kjaer, Svend, Swanton, Charles, Gandhi, Sonia, Beale, Rupert, Gamblin, Steve J, McCauley, John W, Daniels, Rodney Stuart, Howell, Michael, Bauer, David, Nastouli, Eleni, Kassiotis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352583/
https://www.ncbi.nlm.nih.gov/pubmed/34323691
http://dx.doi.org/10.7554/eLife.69317