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Galectin-9 regulates the threshold of B cell activation and autoimmunity

Despite the mechanisms of central and peripheral tolerance, the mature B cell compartment contains cells reactive for self-antigen. How these cells are poised not to respond and the mechanisms that restrain B cell responses to low-affinity endogenous antigens are not fully understood. Here, we demon...

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Detalles Bibliográficos
Autores principales: Smith, Logan K, Fawaz, Kareem, Treanor, Bebhinn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352593/
https://www.ncbi.nlm.nih.gov/pubmed/34369876
http://dx.doi.org/10.7554/eLife.64557