External validation of clinical prediction models: simulation-based sample size calculations were more reliable than rules-of-thumb

INTRODUCTION: Sample size “rules-of-thumb” for external validation of clinical prediction models suggest at least 100 events and 100 non-events. Such blanket guidance is imprecise, and not specific to the model or validation setting. We investigate factors affecting precision of model performance es...

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Detalles Bibliográficos
Autores principales: Snell, Kym I.E., Archer, Lucinda, Ensor, Joie, Bonnett, Laura J., Debray, Thomas P.A., Phillips, Bob, Collins, Gary S., Riley, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352630/
https://www.ncbi.nlm.nih.gov/pubmed/33596458
http://dx.doi.org/10.1016/j.jclinepi.2021.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352630/
https://www.ncbi.nlm.nih.gov/pubmed/33596458
http://dx.doi.org/10.1016/j.jclinepi.2021.02.011

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