An open-source drug discovery platform enables ultra-large virtual screens

On average, an approved drug today costs $2–3 billion and takes over ten years to develop(1). In part, this is due to expensive and time-consuming wet-lab experiments, poor initial hit compounds, and the high attrition rates in the (pre-)clinical phases. Structure-based virtual screening (SBVS) has...

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Detalles Bibliográficos
Autores principales: Gorgulla, Christoph, Boeszoermenyi, Andras, Wang, Zi-Fu, Fischer, Patrick D., Coote, Paul, Das, Krishna M. Padmanabha, Malets, Yehor S., Radchenko, Dmytro S., Moroz, Yurii S., Scott, David A., Fackeldey, Konstantin, Hoffmann, Moritz, Iavniuk, Iryna, Wagner, Gerhard, Arthanari, Haribabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352709/
https://www.ncbi.nlm.nih.gov/pubmed/32152607
http://dx.doi.org/10.1038/s41586-020-2117-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352709/
https://www.ncbi.nlm.nih.gov/pubmed/32152607
http://dx.doi.org/10.1038/s41586-020-2117-z

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